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Exatecan cas 171335-80-1 CAS NO.171335-80-1
- FOB Price: USD: 298.00-998.00 /Gram Get Latest Price
- Min.Order: 0 Metric Ton
- Payment Terms: L/C
- Available Specifications:
1mg(0-1)Gram10mg(1-10)Gram
- Product Details
Keywords
- DX 8951
- Dx 8951
- Exatecan mesylate
Quick Details
- ProName: Exatecan cas 171335-80-1
- CasNo: 171335-80-1
- Application: Inhibitor
- ProductionCapacity: 10 Kilogram/Week
- Purity: 98%
- LimitNum: 0 Metric Ton
Superiority
Exatecan mesylate is a semisynthetic, water-soluble derivative of camptothecin with antineoplastic activity. Exatecan mesylate inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA and inhibiting religation of DNA breaks, thereby inhibiting DNA replication and triggering apoptotic cell death. This agent does not require enzymatic activation and exhibits greater potency than camptothecin and other camptothecin analogues.
Details
Exatecan mesylate is a semisynthetic, water-soluble derivative of camptothecin with antineoplastic activity. Exatecan mesylate inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA and inhibiting religation of DNA breaks, thereby inhibiting DNA replication and triggering apoptotic cell death. This agent does not require enzymatic activation and exhibits greater potency than camptothecin and other camptothecin analogues. #