United States
Premiumsupplier
(S,R,S)-AHPC CAS NO.1448297-52-6
- Min.Order: 0 Metric Ton
- Payment Terms: L/C
- Product Details
Keywords
- cas 1448297-52-6
- 1448297-52-6
- MDK7526
Quick Details
- ProName: (S,R,S)-AHPC
- CasNo: 1448297-52-6
- Molecular Formula: C22H30N4O3S
- Application: Research use
- PackAge: according to the clients requirement
- ProductionCapacity: Metric Ton/Day
- Purity: ≥98%
- Transportation: by sea or by air
- LimitNum: 0 Metric Ton
Superiority
(S,R,S)-AHPC (MDK7526) is the VH032-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC (MDK7526) can be connected to the ligand for protein (e.g., BCR-ABL1) by a linker to form PROTACs (e.g., GMB-475). GMB-475 induces the degradation of BCR-ABL1 with an IC50 of 1.11 μM in Ba/F3 cells. #
Details
(S,R,S)-AHPC (MDK7526) is the VH032-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC (MDK7526) can be connected to the ligand for protein (e.g., BCR-ABL1) by a linker to form PROTACs (e.g., GMB-475). GMB-475 induces the degradation of BCR-ABL1 with an IC50 of 1.11 μM in Ba/F3 cells. #